Education and Work

•Assistant Professor (Jul 2014 – present) 

Institute of Biophysics, Chinese Academy of Sciences, China

•Ph.D.  (Sep 2009 – Jun 2014) in Radiation Medicine

  Supervised by Prof. Fan Wang, Medical School of Peking University

•B.M.    (Sep 2005 – Jun 2009) in Biology, Jilin University

Major Publications

•(99m)Tc-labeled dimeric octreotide Peptide: a radiotracer with high tumor uptake for single-photon emission computed tomography imaging of somatostatin receptor subtype 2-positive tumors. Mol Pharm. 2013 Aug 5;10(8):2925-33.

Chengyan Dong, Huiyun Zhao, Sujuan Yang, Jiyun Shi, Jinming Huang, Liyang Cui, Lijun Zhong, Xiaona Jin,

Fang Li, Fan Wang*.

•Synthesis of poly(ethylene glycol)-b-poly(N-(2-hydroxypropyl) methacrylamide) block copolymers with well-defined structures and their influence on in vivo circulation and biodistribution. Polym Chem. 2014, 5, 5617-5627. 

Qingsong Yu‡, Chengyan Dong‡, Jiajing Zhang, Jiyun Shi, Bing Jia, Fan Wang* and Zhihua Gan*

•Peptide-based radiopharmaceuticals for targeted tumor therapy.  Curr Med Chem. 2014;21(1):139-52.

Chengyan Dong, Zhaofei Liu*, Fan Wang*. (review)

•SPECT/NIRF dual modalityimaging for detection of orthotopic colon tumor with an avidin/biotin pretargeting system.  Sci Rep. 2015; - in submission.

Chengyan Dong, Sujuan Yang, Jiyun Shi, Huiyun Zhao, Lijun Zhong, Zhaofei Liu, Bing Jia*, Fan Wang

•Gefitinib pre-treatment increases the tumor uptake of 99mTc-3PRGD2.  Nucl Med Biol. 2015; - in submission.

Chengyan Dong, Hao Liu, Huiyun Zhao, Jiyun Shi, Bing Jia*, Fan Wang

•Radioligand saturation binding for quantitative analysis of ligand–receptor interactions.  Biophysics Reports. 2015; - in submission.

Chengyan Dong, Zhaofei Liu*, Fan Wang*. (protocol)

Other Publications

•Microarray Based Screening of Peptide Nano Probes for HER2 Positive Tumor. Anal Chem. 2015 Aug 18;87(16):8367-72.

Wang Z, Wang W, Bu X, Wei Z, Geng L, Wu Y, Dong C, Li L, Zhang D, Yang S, Wang F, Lausted C, Hood L, Hu Z.

•Anti-tumor effect of integrin targeted (177)Lu-3PRGD2 and combined therapy with Endostar. Theranostics. 2014 Jan 18;4(3):256-66.

Shi J, Fan D, Dong C, Liu H, Jia B, Zhao H, Jin X, Liu Z, Li F, Wang F.

•Technetium 99m-labeled VQ peptide: a new imaging agent for the early detection of tumors or premalignancies. Mol Imaging. (2013) Jul-Aug;12(5):318-26.

   Shi J, Cui L, Jia B, Liu Z, He P, Dong C, Jin X, Zhao H, Li F, Wang F.

•Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by liver X receptor α through a sterol regulatory element-binding protein 1c-dependent mechanism in mice. Hepatology. 2013 Aug;58(2):617-28.

   Wu J, Wang C, Li S, Li S, Wang W, Li J, Chi Y, Yang H, Kong X, Zhou Y, Dong C, Wang F, Xu G, Yang J, Gustafsson JÅ, Guan Y.

•NaGdF4 nanoparticle-based molecular probes for magnetic resonance imaging of intraperitoneal tumor xenografts in vivo. ACS Nano. 2013 Jan 22;7(1):330-8.

   Hou Y, Qiao R, Fang F, Wang X, Dong C, Liu K, Liu C, Liu Z, Lei H, Wang F, Gao M.

•Noninvasive detection of human-induced pluripotent stem cell (hiPSC)-derived teratoma with an integrin-targeting agent (99m)Tc-3PRGD2. Mol Imaging Biol. 2013 Feb;15(1):58-67.

   Li Y, Liu Z, Dong C, He P, Liu X, Zhu Z, Jia B, Li F, Wang F.

•99mTc-labeled RGD-BBN peptide for small-animal SPECT/CT of lung carcinoma. Mol Pharm. (2012) May 7;9(5):1409-17

   Liu Z, Huang J, Dong C, Cui L, Jin X, Jia B, Zhu Z, Li F, Wang F.

Awards

• Guanghua Scholarship---Peking University                   2011

• Sanhao Award(Straight A student)‐‐‐Peking University        2012

• First-class scholarship‐‐‐Peking University                   2012

• Innovation Award‐‐‐Peking University                   2013

• National Scholarship                                                       2013

• Best Graduate‐‐‐Peking University                           2014

• Best Graduate‐‐‐Beijing City                                   2014

• Top 10 Academic Postgraduate‐‐‐Peking University   2014